Process for recovering residue from glibenclamide synthesis process
The invention provides a process for recovering residue from a glibenclamide synthesis process. The process comprises the following steps: 1) adding a solvent into the residue in a mass volume ratio of 1:100-1:200 and stirring sufficiently; 2) filtering and collecting insoluble matters; 3) drying ti...
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Sprache: | eng |
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Zusammenfassung: | The invention provides a process for recovering residue from a glibenclamide synthesis process. The process comprises the following steps: 1) adding a solvent into the residue in a mass volume ratio of 1:100-1:200 and stirring sufficiently; 2) filtering and collecting insoluble matters; 3) drying till the water content is less than 5% and collecting the dried product. The solvent is any one of methanol, ethanol and isopropanol. The recovery process has the advantages that most of the compound I in the residue can be recovered, meanwhile, the quantity of other impurities is reduced, the recovered compound I can be continuously used for production so as to greatly reduce the production cost, and the process is simple and convenient in operation and convenient to use. |
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