Method of purifying taxane-type derivative

The invention discloses a method of purifying taxane-type derivative cabazitaxel, wherein the method includes steps of dissolving, stirring, crystallization and washing with cabazitaxel being higher than 98% in purity as a raw material. The purified cabazitaxel is higher than 99.6% in purity and is...

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Hauptverfasser: CHE XIN, LANG YUEWU, LIU KE, HU DAIQIANG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention discloses a method of purifying taxane-type derivative cabazitaxel, wherein the method includes steps of dissolving, stirring, crystallization and washing with cabazitaxel being higher than 98% in purity as a raw material. The purified cabazitaxel is higher than 99.6% in purity and is less than 0.1% in the content of single impurity. The method is simple in operations and is suitable for industrialized production.