Preparation method of oily fluconazole injection for pets

The invention relates to a preparation method of oily fluconazole injection for pets. The preparation method comprises the following steps: at first, carrying out dry heat sterilization on injection castor oil at 150 DEG C for 2 hours, cooling to 50 DEG C, dissolving fluconazole and butyl hydroxy an...

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Sprache:eng
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Zusammenfassung:The invention relates to a preparation method of oily fluconazole injection for pets. The preparation method comprises the following steps: at first, carrying out dry heat sterilization on injection castor oil at 150 DEG C for 2 hours, cooling to 50 DEG C, dissolving fluconazole and butyl hydroxy anisd in a mixed solution of glyceryl triacetate and absolute ethyl alcohol, adding 1,2-propylene glycol for mixing, slowly adding the sterilized injection castor oil, stirring uniformly, filtering the prepared solution via a microfiltration membrane, and packaging the product in a sterilized penicillin bottle to obtain stable oily fluconazole injection for pets. The preparation process is simple and the cost is low, so that the commercialization prospect is good.