Preparation method of 2, 4-dimethyl-6-(1-methyl-pentadecyl) phenol

The invention discloses a preparation method of 2, 4-dimethyl-6-(1-methyl-pentadecyl) phenol. The method takes 2, 4-dimethyl phenol and hexadecane as raw materials, and comprises the steps of putting the 2, 4-dimethyl phenol and the hexadecane into a reactor according to the batch charge that molar ratio of the 2, 4-dimethyl phenol to the hexadecane is equal to (1.0-1.5): 1; feeding a sulfuric acid catalyst loaded on activated carbon into the reactor, wherein the dosage of the catalyst is 5-20% of the mass of the hexadecane; under the protection of nitrogen, mixing and heating up to 100-160 DEG C, carrying out reaction for 8-30 hours, and filtering to obtain a solid catalyst; carrying out reduced pressure distillation on filtrate to obtain unreacted raw materials; after that, carrying out reduced pressure distillation at the temperature of 180-200 DEG C under 1-2mmHg to obtain the 2, 4-dimethyl-6-(1-methyl-pentadecyl) phenol. Compared with the existing synthesis method, the preparation method has the product yield reaching up to more than 88% and the content reaching up to more than 96%. The preparation method of the 2, 4-dimethyl-6-(1-methyl-pentadecyl) phenol has the advantages of being mild in reaction conditions, fewer in side reactions, reusable in catalyst, etc.