Hyperbranched polyglycerol modified latex microsphere enhanced immunoturbidimetry and application thereof

The invention discloses hyperbranched polyglycerol modified latex microsphere enhanced immunoturbidimetry and an application thereof. A latex microsphere material which is hydrophilic on surface and is rich in functional groups is prepared by using the hyperbranched polyglycerol modified latex micro...

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Bibliographische Detailangaben
Hauptverfasser: LUO YASAI, TONG LIU, SU ENBEN, JIN JING, ZHU ZONGZHE
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses hyperbranched polyglycerol modified latex microsphere enhanced immunoturbidimetry and an application thereof. A latex microsphere material which is hydrophilic on surface and is rich in functional groups is prepared by using the hyperbranched polyglycerol modified latex microspheres. In actual use, when an immunoturbidimetric reagent of the hyperbranched polyglycerol modified latex microspheres is used, the reagent can be used for inhibiting nonspecific adsorption of proteins well and the antibody coupling rate is further higher than that of common commercialized latex microspheres. In project performance analysis, the latex microsphere reagent can be used for greatly enhancing reaction between antigens and antibodies. Compared with common commercialized latex microsphere reagents, the latex microsphere reagent has the advantages that the sensitivity and detection range are obviously improved and the hyperbranched polyglycerol modified latex microsphere enhanced immunoturbidimetry has excellent performances of relevance, stability and repeatability.