Method for synthesizing 2-methyl-4,5-diphenylimidazole and 2,3,4-triphenyl-oxazole
The invention provides a new method for synthesizing 2-methyl-4,5-diphenylimidazole and 2,3,4-triphenyl-oxazole in a reaction system at the same time. Benzil, butanedione and ammonium acetate with the molar ratio of 1:3:10 are added in absolute ethyl alcohol, after even stirring, the mixture is heat...
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Sprache: | eng |
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Zusammenfassung: | The invention provides a new method for synthesizing 2-methyl-4,5-diphenylimidazole and 2,3,4-triphenyl-oxazole in a reaction system at the same time. Benzil, butanedione and ammonium acetate with the molar ratio of 1:3:10 are added in absolute ethyl alcohol, after even stirring, the mixture is heated to 70-78 DEG C, the reaction solution is insulated till the reaction is finished, a reflux unit is changed into a distillation device, after solvent is steamed away, and the thin layer chromatography is carried out on residues to obtain 2-methyl-4,5-diphenylimidazole and 2,3,4-triphenyl-oxazole through separation. The method for synthesizing 2-methyl-4,5-diphenylimidazole and 2,3,4-triphenyl-oxazole is easy to operate and has high practical value. |
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