Method for preparing n-phenylglycinenitrile

The invention relates to a method for preparing n-phenylglycinenitrile. The method is characterized in that condensation reaction is continuously performed for aniline and glycolonitrile by a micro-channel reactor to obtain n-phenylglycinenitrile; the pH of glycolonitrile is pre-regulated to be 1.5...

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Bibliographische Detailangaben
Hauptverfasser: CHENG LIHUA, LIU SHAOHUA, WANG JINJIN, CHEN YINXIA, DONG PU, ZHANG CHENLIANG, PENG YANLI, YANG XUEWEI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to a method for preparing n-phenylglycinenitrile. The method is characterized in that condensation reaction is continuously performed for aniline and glycolonitrile by a micro-channel reactor to obtain n-phenylglycinenitrile; the pH of glycolonitrile is pre-regulated to be 1.5 to 7 through a basic catalyst; the molar ratio of aniline to glycolonitrile is 1.00: 1.00-1.30. The method for preparing n-phenylglycinenitrile has the advantages that the process route is simple, and the reaction is fast, so that the working efficiency and production capacity can be ensured, and moreover, the production and operation safety of the process can also be ensured; with the adoption of the process method, the purity of a n-phenylglycinenitrile product exceeds 98.0% and the yield exceeds 99.9%.