Method for synthesizing primary monohydroxytrimethylsilyl disaccharide
The invention discloses a method for synthesizing primary monohydroxytrimethylsilyl disaccharide and belongs to the technical field of chemical synthesis. The process comprises the following steps: taking ammonium acetate as a selective removal agent of trimethylsilyl at room temperature, taking a d...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The invention discloses a method for synthesizing primary monohydroxytrimethylsilyl disaccharide and belongs to the technical field of chemical synthesis. The process comprises the following steps: taking ammonium acetate as a selective removal agent of trimethylsilyl at room temperature, taking a disaccharide subjected to full trimethylsilyl protection as a substrate, stirring and reacting in an organic solvent, selectively removing one trimethylsilyl at the primary position of the disaccharide, thereby obtaining the primary monohydroxytrimethylsilyl disaccharide. The method disclosed by the invention is mild in reaction conditions, high in region selectivity and high in yield and is applied to scientific research and development and large-scale production. |
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