Chitosan hemostatic material formed through covalent crosslinking and preparation method thereof

The invention discloses a chitosan hemostatic material formed through covalent crosslinking and a preparation method thereof. The chitosan hemostatic material formed through covalent crosslinking is obtained by covalently crosslinking chitosan by utilizing a crosslinking agent, wherein the crosslinking agent is 1,4-butanediol diglycidyl ether. The preparation method of the chitosan hemostatic material formed through covalent crosslinking comprises the following steps: 1) preparing chitosan into a water solution; 2) adding the crosslinking agent to the chitosan water solution, fully stirring and mixing the materials, then pouring the mixture into a mold, and drying the product, thus obtaining the chitosan hemostatic material, wherein the crosslinking agent is 1,4-butanediol diglycidyl ether. The chitosan hemostatic material and the preparation method have the beneficial effects that chitosan is crosslinked by 1,4-butanediol diglycidyl ether under acidic conditions; an ethylene oxide group in 1,4-butanediol diglycidyl ether carries out ring-opening reaction with hydroxyl on chitosan under acidic conditions to form the crosslinked product by generating ether bonds; the crosslinking agent used in the method is relatively safe; the preparation process is simple and practicable and is lower in production cost.