Vaccine for inhibiting streptococcus and/or preventing streptococcus infection

The invention discloses a vaccine for inhibiting streptococcus and/or preventing streptococcus infection. Active components of the vaccine provided in the invention comprise a component A and a component B; the component A comprises a sortase, a fusion protein containing the sortase, protein formed by conjugated connection of the sortase with adjuvant protein, a connection compound of the sortase and polysaccharide or a DNA expression vector of a coding gene of the sortase; the component B comprises a cholera toxin B subunit and fusion protein containing the cholera toxin B subunit. The vaccine provided in the invention has the superiority of high efficiency, wide spectrum, and low cost. Meanwhile, the vaccine provided in the invention adopts a mucosal immunization approach, has the characteristics of no tissue damage, no local side effect, and simple usage, and is suitable for popularization and application.