Aptamer for periostin and anti-cancer composition including same

The present invention provides a DNA aptamer specifically binding to periostin, a composition for inhibiting cancer and/or cancer metastasis, and a composition for diagnosing cancer and/or cancer metastasis, wherein the composition contains the DNA aptamer as an active ingredient. The aptamer is cha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	XU PANJI, JIN RUNDONG, LIN ZHONGXUN, JIN YIXIN, CAI RONGCAN, LI YOUZHEN, LIU CHENGHAO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a DNA aptamer specifically binding to periostin, a composition for inhibiting cancer and/or cancer metastasis, and a composition for diagnosing cancer and/or cancer metastasis, wherein the composition contains the DNA aptamer as an active ingredient. The aptamer is characterized in that it has a binding mechanism that differs from conventional antibodies, thus making it possible to more effectively inhibit and diagnose cancer/cancer metastasis.