Polypeptide loaded poca nanoparticles for oral administration
The disclosure relates to nanoparticles comprising poly(octylcyanoacrylate) for oral administration of a biologically active polypeptide, in particular a metabolic peptide, such as exendin-4. Also disclosed are methods of producing such nanoparticles, pharmaceutical compositions comprising such nano...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The disclosure relates to nanoparticles comprising poly(octylcyanoacrylate) for oral administration of a biologically active polypeptide, in particular a metabolic peptide, such as exendin-4. Also disclosed are methods of producing such nanoparticles, pharmaceutical compositions comprising such nanoparticles and methods of treating metabolic disorders, such as obesity, using such nanoparticles. |
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