Method for high density fermentation of spinosad

The invention relates to a method for high density fermentation of spinosad. The invention provides a method for culturing eukaryotic microorganisms. The method includes strain mutagenesis and gene screening, medium improvement, precise control and improvement of fermentation process, and improvemen...

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Bibliographische Detailangaben
Hauptverfasser: GE YONG, ZHANG LANBO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a method for high density fermentation of spinosad. The invention provides a method for culturing eukaryotic microorganisms. The method includes strain mutagenesis and gene screening, medium improvement, precise control and improvement of fermentation process, and improvement of the extraction process. Accordingly, the fermentation titer of spinosad can reach over 6500mg/L, and the purity of spinosad can reach 98%.