PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS

PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS

Cyhalofop esters are prepared by coupling 2-(4-hydroxyphenoxy)-propionic acid with 3,4-difluorobenzonitrile with base in a polar aprotic solvent (optionally including a phase-transfer catalyst), alkylating with alkyl halide, removing the polar aprotic solvent (optionally using cyhalofop ester as a f...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LENG RONALD B, OTTERBACHER ERIC W, PRAAY HERBERT N
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Cyhalofop esters are prepared by coupling 2-(4-hydroxyphenoxy)-propionic acid with 3,4-difluorobenzonitrile with base in a polar aprotic solvent (optionally including a phase-transfer catalyst), alkylating with alkyl halide, removing the polar aprotic solvent (optionally using cyhalofop ester as a flux), removing salt by aqueous extraction of molten cyhalofop ester without a solvent, and removing residual water by heating under reduced pressure.