Method for synthesizing 2-norbornane ketone
The invention discloses a method for synthesizing 2-norbornane ketone. The method comprises the following steps: reacting 2-norbornane alcohol with oxygen in an organic solvent in the presence of a catalyst and a co-catalyst, wherein the reaction temperature is 70-90 DEG C, the pressure of oxygen is...
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Zusammenfassung: | The invention discloses a method for synthesizing 2-norbornane ketone. The method comprises the following steps: reacting 2-norbornane alcohol with oxygen in an organic solvent in the presence of a catalyst and a co-catalyst, wherein the reaction temperature is 70-90 DEG C, the pressure of oxygen is 0.2-0.6MPa, the reaction time is 1-5 hours, the catalyst is 4-hydroxy-2,2,6,6-tetramethyl piperidine-nitrogen-oxide, and the co-catalyst consists of nitrous acid tert-butyl ester and cuprous chloride; and after the reaction is completed, filtering out cuprous chloride, performing vacuum spinning evaporation on the reaction liquid at 30-60 DEG C till the weight is constant, separating the nitrous acid tert-butyl ester on the lower layer by using a separating funnel, and distilling the product on the upper layer by using steam, thereby obtaining 2-norbornane ketone. |
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