Triazole antifungal compound and salt thereof

The invention relates to a novel triazole compound having an antifungal effect. The triazole compound has the chemical structural formula represented by the general formula (1): Ar represents phenyl or phenyl with 1-3 substituent groups, wherein the substituent groups are halogen atom or trifluorome...

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Bibliographische Detailangaben
Hauptverfasser: ZHENG CANHUI, JIANG JUNHANG, LYU JIAGUO, ZHU JU, WANG ZHENG, LIU NA, ZHOU YOUJUN, WEI HAIYANG
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to a novel triazole compound having an antifungal effect. The triazole compound has the chemical structural formula represented by the general formula (1): Ar represents phenyl or phenyl with 1-3 substituent groups, wherein the substituent groups are halogen atom or trifluoromethyl; R1 represents pyridyl, pyrimidyl, pyrazinyl, pyridazinyl or triazinyl; R2 represents oxygen atom or sulfur atom; R3 represents halogen atom, hydrogen atom, lower alkyl, lower alkoxy, carboxylic acid esters with different substituents, carboxyl, cyano group or acyl; the relative position of R3 to R2 is an ortho-position, a meta-position or a para-position, and R3 can be monosubstituted or polysubstituted. The triazole compound shows quite strong antifungal activity, and can be used for preparation of antifungal drugs.