Diphenol compound in tobacco rhizome and preparation method and application thereof

The invention discloses a diphenol compound (I) in tobacco rhizome and a preparation method and application thereof. Tobacco whole plant is crushed, and then ultrasonically extracted with methanol, the extracted liquid is merged, filtered, and concentrated under vacuum into extract; the extract is p...

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Hauptverfasser: MIAO MINGMING, ZHANG FENGMEI, ZHANG TAO, CHEN ZHANGYU, YANG GUANGYU, LIU ZHIHUA, SHANG SHANZHAI, ZHAO WEI, WANG LAN, LIU CHUNBO, SHEN QINPENG
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a diphenol compound (I) in tobacco rhizome and a preparation method and application thereof. Tobacco whole plant is crushed, and then ultrasonically extracted with methanol, the extracted liquid is merged, filtered, and concentrated under vacuum into extract; the extract is primarily separated by silica gel column chromatography; a chloroform-acetone solution with the volume ratio of 1:0 to 1:2 is used for gradient elution; eluent 7:3 part is further separated and purified by high pressure liquid chromatography to obtain the required diphenol compound. The experiment proves that the biphenyl compound has good inhibition effect on tobacco mosaic virus, and can be used as a lead compound against the tobacco mosaic virus.