Polyacrylonitrile/cellulose acetate fiber composite hemodialysis membrane and preparation method thereof

The invention discloses a polyacrylonitrile/cellulose acetate fiber composite hemodialysis membrane and a preparation method thereof, and relates to the field of biological materials. The hemodialysis membrane refers to a hollow fiber membrane, the average inner diameter of hollow fibers is 122-245 microns, and the wall thickness is 22-50 microns. The hemodialysis membrane comprises the following components in parts by mass: 35-60 parts of polyacrylonitrile fibers, 25-40 parts of cellulose acetate fibers, 3-7 parts of a coupling agent and 30-60 parts of solvents, wherein the solvents refer to acetone and DMAC or acetone and DMSO. In the method for preparing the polyacrylonitrile/cellulose acetate fiber composite hemodialysis membrane, a dry-wet preparation process is adopted. The polyacrylonitrile/cellulose acetate fiber composite hemodialysis membrane provided by the invention is relatively high in retention rate of bovine serum albumin, relatively high in biocompatibility, relatively high in permeability on vitamin B12 and relatively low in cost and is a relatively ideal hemodialysis membrane material.