Large-thickness and high-strength steel plate applicable to low temperature and manufacturing method thereof

The invention discloses a large-thickness and high-strength steel plate applicable to low temperature. The steel plate comprises the following chemical components in percentage by mass: 0.08-0.15% of C, 0.15-0.35% of Si, 0.95-1.25% of Mn, smaller than or equal to 0.01% of P, smaller than or equal to 0.005% of S, 0.35-0.55% of Cr, 0.35-0.55% of Mo, 0.88-1.5% of Ni, 0.20-0.40% of Cu, 0.02-0.08% of Al, 0.03-0.05% of V, 0.02-0.04% of Nb, smaller than or equal to 0.02% of Ti, smaller than or equal to 0.006% of N, 0.0008-0.002% of B and the balance of Fe and inevitable impurity elements. The manufacturing method of the steel plate adopts the following process flows: smelting and continuously casting, slowly cooling by covering, clearing at a certain temperature, heating, rolling, performing air cooling and straightening, slowly cooling, and quenching and tempering. The manufactured steel plate has the thickness of 80-125mm, has high strength, good ductility and high low-temperature toughness, can be adapted to a minus 60 DEG C low-temperature environment, can meet a requirement on high Z-direction performance, and has excellent overall performance.