Method for preparing polyglycolic acid/hydroxyapatite composite biological ceramic material

The invention provides a method for preparing a polyglycolic acid/hydroxyapatite composite biological ceramic material. The method comprises the following steps: (1) dissolving polyglycolic acid, a surfactant and a cosurfactant into an organic solvent, so as to prepare an oil-phase solution of polyg...

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Bibliographische Detailangaben
Hauptverfasser: YU GUOZHEN, OUYANG ZHIKUN, JIN ZHONGEN
Format: Patent
Sprache:eng
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Zusammenfassung:The invention provides a method for preparing a polyglycolic acid/hydroxyapatite composite biological ceramic material. The method comprises the following steps: (1) dissolving polyglycolic acid, a surfactant and a cosurfactant into an organic solvent, so as to prepare an oil-phase solution of polyglycolic acid; (2) respectively adding a calcium ion solution and a phosphate ion solution into the oil-phase solution, so as to prepare an emulsion and a phosphate ion emulsion, mixing the calcium ion emulsion and the phosphate ion emulsion, and reacting for 12-24 hours at the temperature of 50-80 DEG C, so as to form a polyglycolic acid/hydroxyapatite mixed emulsion; (3) volatilizing the organic solvent in the mixed emulsion prepared in the step (2), washing with water, drying, so as to obtain powder, and sintering the obtained powder in a spark plasma sintering chamber. The composite biological ceramic material prepared by the method is good in dispersity, high in mechanical strength, relatively lower in reaction temperature, higher in bioavailability and safer in production, and hydroxyapatite cannot be degraded.