Isoxazole beta-lactamase inhibitors

beta-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D beta-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also...

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Bibliographische Detailangaben
Hauptverfasser: BUSCH ROBERT, ALEXANDER DYLAN C, METCALF CHESTER A III, GU YUGUI, YIN NING, HE YONG, CROSS JASON B
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:beta-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D beta-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.