Indole-containing amine compounds, and preparation method and application thereof

The invention discloses indole amine compounds and pharmaceutically acceptable salts thereof. The compounds have favorable activities for inhibiting tumors from generation and transfer, have obvious inhibiting actions on mammary cancer cells, are excellent antitumor lead compounds, can be further de...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KONG YA, LIU PANHE, LU ZONGLIANG, XU HONGXIA, LI YANWU, ZHU TAIYONG
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention discloses indole amine compounds and pharmaceutically acceptable salts thereof. The compounds have favorable activities for inhibiting tumors from generation and transfer, have obvious inhibiting actions on mammary cancer cells, are excellent antitumor lead compounds, can be further developed into antineoplastic drugs for tumor metastasis, advanced tumors, nonsolid tumors and other cancers, and has potential and wide application prospects in the field of tumor therapy. The compounds are prepared by carrying out amine alkylation reaction on the halogenation part and primary amine part in a DMSO (dimethyl sulfoxide) solvent; and the method is simple and suitable for industrial production.