Method for determining glucose concentration in human blood

The method involves measuring the impedance of a human body region at a high frequency (Z HF ) and a low frequency (Z LF ) with the aid of electrodes fastened to the human body. The value Z HF is used to obtain the value of the volume of fluid contained in the tissues of the human body region. The v...

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Hauptverfasser: SOKOLOV EVGENIY L VOVICH, ELOKHOVSKIY VLADIMIR YUR EVICH, CHECHIK ANDREY ANATOL EVICH
Format: Patent
Sprache:eng
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Zusammenfassung:The method involves measuring the impedance of a human body region at a high frequency (Z HF ) and a low frequency (Z LF ) with the aid of electrodes fastened to the human body. The value Z HF is used to obtain the value of the volume of fluid contained in the tissues of the human body region. The value Z LF is used to obtain the value of the volume of extracellular fluid contained in the tissues of the human body region. The amount of increase in the metabolic component in the volume of extracellular fluid which is related to the synthesis and utilization of energy carriers in the human body is determined by determining the increase in the value of the volume of all of the fluid in comparison with the previous measurement, determining the increase in the value of the volume of extracellular fluid in comparison with the previous measurement and subsequently calculating the difference between the aforesaid increases in the value of the volume of all of the fluid and the value of the volume of extracellular fluid. The amount of increase in the glucose concentration is determined by normalizing the above-mentioned amount of increase in the metabolic component in the volume of extracellular fluid. The glucose concentration in human blood G(t k ) is determined by adding the above-mentioned amount of increase in the glucose concentration and the value of the glucose concentration in the blood determined at the previous measuring stage. The method enables a highly accurate, non-invasive determination of the glucose concentration in human blood.