Glucagon-like peptide 1 (GLP-1) pharmaceutical formulations

The invention relates to glucagon-like peptide 1 (GLP-1) pharmaceutical formulations. Specifically, the invention discloses a composition which is table both in vivo and in vitro. The composition comprises glucagon-like peptide 1 (GLP-I) particles in combination with diketopiperazine (DKP). The comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	FARIS MARY, GREENE STEPHANIE, HOKENSON MARK J, GELBER COHAVA, LEONE-BAY ANDREA, OBERG KEITH, BRANDT DAVID, KING MARK, CHEATHAM WAYMAN WENDELL
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to glucagon-like peptide 1 (GLP-1) pharmaceutical formulations. Specifically, the invention discloses a composition which is table both in vivo and in vitro. The composition comprises glucagon-like peptide 1 (GLP-I) particles in combination with diketopiperazine (DKP). The composition can be used as a pharmaceutical formulation for treating diseases such as diabetes, cancers, and obesity but is not limited to such diseases or conditions. In particularly, the composition can be used as a pharmaceutical formulation for pulmonary delivery.