Function and application of autophagy-related genes ATG10 to participation of RNA virus replication

The invention relates to a new function of influences of genes and protein of autophagy-related genes ATG10 of a person on RNA virus replication and application thereof. In particular, two overall-length code area (CDS) sequences of the autophagy-related genes ATG10 of the person, control region seq...

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Bibliographische Detailangaben
Hauptverfasser:	ZHAO QIONG, HU ZHANYING, ZHANG JINGPU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a new function of influences of genes and protein of autophagy-related genes ATG10 of a person on RNA virus replication and application thereof. In particular, two overall-length code area (CDS) sequences of the autophagy-related genes ATG10 of the person, control region sequences (involving but not limited to a promoter sequence, a first intron sequence, a second intron sequence, a third intron sequence and a fourth intron sequence) of the overall-length code area (CDS) sequences and two ATG10 protein molecules ATG10-L and ATG10-S are used as target spots or target objects, wherein the two ATG10 protein molecules ATG10-L and ATG10-S are translated by two coded sequences of the autophagy-related genes ATG10 and comprise sequence analogs, microRNAs and the like; a new RNA-virus-resisting protein medicine and related new products are researched and developed through genetic manipulation, screening, pronucleus and eukaryotic cell gene expressions and the like. A candidate compound of the new RNA-virus-resisting medicine with a new effecting target spot is researched and developed by screening compounds capable of controlling two ATG10 protein difference expressions.