Preparation method of simvastatin tablet

The invention relates to a preparation method of a simvastatin tablet. The simvastatin tablet is composed of simvastatin, an acidic protecting agent, an antioxidant agent, a filling agent, a disintegrating agent and a lubricant. The preparation method disclosed by the invention comprises the following steps: carrying out low-temperature superfine grinding on a simvastatin raw material and lactose in a weight ratio of 1 to (1-10), so that the particle size is reduced and the specific surface area is increased, and then the raw material is changed from a lipophilic material into a hydrophilic material; uniformly mixing the obtained mixed material with the acidic protecting agent and the antioxidant agent, the rest of lactose, microcrystalline celluloses and crosslinked carboxymethyl cellulose sodium, granulating by using a wet method, and carrying out fluidized drying while controlling the water content of a finished product grains at 1-5%, so that the simvastatin tablet is prepared. The prescription process is