Application of beta-arrestin-1 in preparing medicine for preventing or treating myocardial infarction

The invention relates to the technical field of medicines, and provides a new application of a beta-arrestin-1 protein. The new application is the application of the beta-arrestin-1 in preparing a medicine or a health care product for preventing or treating myocardial infarction. Experiments prove t...

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Bibliographische Detailangaben
Hauptverfasser: KE PING, LIU CHONG, SHAO BAIZONG, SU DINGFENG, XU ZHEQI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of medicines, and provides a new application of a beta-arrestin-1 protein. The new application is the application of the beta-arrestin-1 in preparing a medicine or a health care product for preventing or treating myocardial infarction. Experiments prove that the myocardial infarction area of a mouse is outstandingly increased after the beta-arrestin-1 is knockout, the myocardial infarction area is outstandingly decreased after the beta-arrestin-1 is extremely expressed; in addition, left ventricular ejection fraction and left ventricular fractional shortening are obviously lower than those of a wild type mice group after the beta-arrestin-1 is knockout, and the left ventricular ejection fraction and the left ventricular fractional shortening are outstandingly enhanced after the beta-arrestin-1 is extremely expressed. Thus, the beta-arrestin-1 plays a protective role in the prognosis of the myocardial infarction.