Compound ketoconazole ointment and preparation method thereof

The invention discloses compound ketoconazole ointment and a preparation method thereof. The preparation method comprises the following steps: uniformly mixing an oil phase and a water phase at 60-100 DEG C, and cooling to form ointment, thereby obtaining the compound ketoconazole ointment, wherein the oil phase contains oil phase matrix and polyethylene glycol-7-stearate; the water phase contains ketoconazole, clobetasol propionate, moisture absorbent, essence and purified water. The preparation method is simple and convenient in process, low in production cost and capable of avoiding product instability caused by a production process; the compound ketoconazole ointment disclosed by the invention can meet the legal standards in aspects such as the shape, the identification, the packing volume, the marking volume and the microbial limit, and is excellent in acceleration stability and long-term stability, and moreover, the ointment of a product is appropriate in concentration and convenient to use.