Metalnikowin-like antibacterial peptide and application thereof

The invention discloses a Metalnikowin-like antibacterial peptide and application thereof, belonging to the technical field of molecular biology. The Metalnikowin-like antibacterial peptide consists of 23 amino acids, the amino acid sequence of the Metalnikowin-like antibacterial peptide is as shown...

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Bibliographische Detailangaben
Hauptverfasser: WANG CHEN, GUO XIANGLING, LI XIAOKANG, NIU MINGMEI, WU TINGCAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a Metalnikowin-like antibacterial peptide and application thereof, belonging to the technical field of molecular biology. The Metalnikowin-like antibacterial peptide consists of 23 amino acids, the amino acid sequence of the Metalnikowin-like antibacterial peptide is as shown in SEQ ID NO.1, and the molecular weight of the Metalnikowin-like antibacterial peptide is 2742.17Da. The antibacterial peptide can be used for inhibiting the growth of bacterium including chicken colibacillosis, swine colibacillosis, salmonella, staphylococcus aureus, pasteurella and the like, has a relatively better antibacterial effect in comparison with antibiotics such as penicillin, streptomycin, cephazolin sodium and azithromycin, and has higher antibacterial activity in comparison with general Metalnikowin antibacterial peptides such as Metalnikowin I, Metalnikowin IIA and Metalnikowin IIB. The minimal antibacterial concentration of the antibacterial peptide against salmonella is 312.5 microgram/mL; the an