Application of ritonavir in preparing medicines for preventing or treating acute lung injury/acute respiratory distress syndrome and pulmonary fibrosis

The invention provides a new medical application of ritonavir and in particular relates to an application of the ritonavir for preventing or treating Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) and pulmonary fibrosis in such a manner of inhibiting the occurrence and development...

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Bibliographische Detailangaben
Hauptverfasser:	JI YUNXIA, KANG ZECHUN, JIANG WANGLIN, LYU CHANGJUN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides a new medical application of ritonavir and in particular relates to an application of the ritonavir for preventing or treating Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) and pulmonary fibrosis in such a manner of inhibiting the occurrence and development of the ALI/ARDS and the pulmonary fibrosis by inhibiting the apoptosis of type I alveolar epithelial cells and promoting the expression of the Receptor For Advanced Glycation Endproducts (RAGE) of the type I alveolar epithelial cells. When in use, the oral administration dosage of the ritonavir ranges from 100mg to 6000mg, preferably, from 200mg to 3000mg.