Self-assembling method of a galactose-containing thermo-sensitive copolymer

The invention relates to a self-assembling method of a galactose-containing thermo-sensitive copolymer. The self-assembling method comprises the following steps: dissolving vinyl adipate galactose ester OVNG and diethylene glycol dimethacrylate DEGMA into a solvent, adding an evocating agent and a c...

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Bibliographische Detailangaben
Hauptverfasser:	SUN KAN, XU MURU, WU HANBING, ZHU LIMIN, LI HEYU, QUAN JING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The invention relates to a self-assembling method of a galactose-containing thermo-sensitive copolymer. The self-assembling method comprises the following steps: dissolving vinyl adipate galactose ester OVNG and diethylene glycol dimethacrylate DEGMA into a solvent, adding an evocating agent and a chain transfer agent, stirring and reacting for 10-15 hours under the protection of nitrogen to obtain a thermo-sensitive copolymer P(DEGMA-co-OVNG); preparing copolymer P (DEGMA-co-OVNG) water solutions with different concentrations, wherein the concentrations range from 0.2mg/ml to 2mg/ml, then, keeping the water solutions at the temperature of 25-50 DEG C to obtain the galactose-containing thermo-sensitive copolymer. By adopting the self-assembling method, through changing temperatures and concentrations, different forms of polymer micelles are formed, and the method has the characteristics of simple operation and obvious effect.