Preparation method of liquid/liquid interface self-assembled silver nanoparticle surface enhanced raman spectroscopy filter paper base

The invention discloses a preparation method of a liquid/liquid interface self-assembled silver nanoparticle surface enhanced raman spectroscopy filter paper base and relates to a preparation method of a silver nanoparticle surface enhanced raman spectroscopy filter paper base for solving the problems that the SERS (Surface Enhanced Raman Scattering) base prepared by the existing method has poor uniformity and stability and low sensitivity. The preparation method comprises the following steps: firstly, adding silver sol and dichloromethane into a centrifuge tube and oscillating to obtain a primary silver nanoparticle film at the water/oil interface position; secondarily, adding tetrabutylammonium nitrate solution to form a silver nanoparticle film; thirdly, removing a water phase and an oil phase to obtain a compact silver nanoparticle film; adsorbing the compact silver nanoparticle film on a piece of filter paper with a coating method, and drying to prepare the surface enhanced raman spectroscopy filter pape