Method Of Determining The Weight Of The Coating To Be Applied To Form Controlled Release Dosage Form

Method Of Determining The Weight Of The Coating To Be Applied To Form Controlled Release Dosage Form

The present invention relates to a method of determining the weight of the coating to be applied to form a controlled release dosage form. A method of coating spherical particles of a beta blocker compound comprises(a) determining the surface area of a weighed sample of said spherical particles; (b)...

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Hauptverfasser: RUBINO ORAPIN, MUELLER OLIVER, JONES DAVID, PRASCH ARMIN, ETTNER ANN, FEMIA ROBERT A, POLLINGER NORBERT, RANGUNATHAN NARAYAN
Format: Patent
Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator RUBINO ORAPIN
MUELLER OLIVER
JONES DAVID
PRASCH ARMIN
ETTNER ANN
FEMIA ROBERT A
POLLINGER NORBERT
RANGUNATHAN NARAYAN
description The present invention relates to a method of determining the weight of the coating to be applied to form a controlled release dosage form. A method of coating spherical particles of a beta blocker compound comprises(a) determining the surface area of a weighed sample of said spherical particles; (b) determining the weight of coating material per surface area unit of spherical particles that will provide a desired release profile for said beta-blocker; (c) determining the surface area of a subsequent batch of spherical particles containing the same beta; (d) coating the subsequent batch of spherical particles with the coating applied in step (b) to provide a coating having substantially the same weight of coating material per surface area unit of spherical particles as determined in step (b).
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Method Of Determining The Weight Of The Coating To Be Applied To Form Controlled Release Dosage Form
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