Method Of Determining The Weight Of The Coating To Be Applied To Form Controlled Release Dosage Form

The present invention relates to a method of determining the weight of the coating to be applied to form a controlled release dosage form. A method of coating spherical particles of a beta blocker compound comprises(a) determining the surface area of a weighed sample of said spherical particles; (b) determining the weight of coating material per surface area unit of spherical particles that will provide a desired release profile for said beta-blocker; (c) determining the surface area of a subsequent batch of spherical particles containing the same beta; (d) coating the subsequent batch of spherical particles with the coating applied in step (b) to provide a coating having substantially the same weight of coating material per surface area unit of spherical particles as determined in step (b).