Phenyl-guanidine derivatives

Provided herein are phenyl-guanidine derivatives for the inhibition of Rac1 which blocks its interaction with guanosine exchange factors (GEFs) belonging to the DBL family as agents for the treatment of aggressive and/or resistant tumours, as well as pharmaceutical compositions comprising them, thei...

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Hauptverfasser: GOMEZ DANIEL EDUARDO, LORENZANO MENNA PABLO, COMIN JULIETA, ALONSO DANIEL FERNANDO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are phenyl-guanidine derivatives for the inhibition of Rac1 which blocks its interaction with guanosine exchange factors (GEFs) belonging to the DBL family as agents for the treatment of aggressive and/or resistant tumours, as well as pharmaceutical compositions comprising them, their use in therapy and processes for their preparation.