Macrolide compound and preparation method thereof and application as marine antifouling agent

The invention discloses a macrolide compound and a preparation method thereof and application as a marine antifouling agent. The macrolide compound is characterized in that a 14-dihydroxy-benzoic acid macrolide compound has a structure in a formula I shown in the specification, wherein R1 and R3 are...

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Bibliographische Detailangaben
Hauptverfasser:	WANG CHANGYUN, SHAO CHANGLUN, LIU QINGAI, WANG KAILING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROCESSES USING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a macrolide compound and a preparation method thereof and application as a marine antifouling agent. The macrolide compound is characterized in that a 14-dihydroxy-benzoic acid macrolide compound has a structure in a formula I shown in the specification, wherein R1 and R3 are OH; R2 and R4 are H; or R1 and R3 are H; R2 and R4 are OH; or R1 and R4 are OH; R2 and R3 are H. The compound in the formula I can be prepared from thalassiomycetes cochliobolus lunatus (TA26-46) by the means of cultivation, fermentation, chromatography separation and the like. The invention provides a natural marine antifouling agent which is high in efficiency and low in toxicity. The marine antifouling agent is characterized in that the compound in the formula I or the salt thereof is taken as an effective ingredient applied to prevention and treatment of fouling of marine organisms caused by barnacle.