Oxidation and amination of secondary alcohols

The invention relates to a method comprising the following steps: a) providing a secondary alcohol; b) oxidizing the secondary alcohol by bringing said alcohol into contact with an NAD(P)+-dependent alcohol dehydrogenase; and c) bringing the oxidation product of step a) into contact with a transamin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PFEFFER JAN CHRISTOPH, POETTER MARKUS, LERCHNER ALEXANDRA, SCHAFFER STEFFEN, HAAS THOMAS, SKERRA ARNE, TAUBER KATHARINA CHRISTIN, SATTLER JOHANN H, KROUTIL WOLFGANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to a method comprising the following steps: a) providing a secondary alcohol; b) oxidizing the secondary alcohol by bringing said alcohol into contact with an NAD(P)+-dependent alcohol dehydrogenase; and c) bringing the oxidation product of step a) into contact with a transaminase, wherein the NAD(P)+-dependent alcohol dehydrogenase and/or the transaminase are/is a recombinant or isolated enzyme. The invention further relates to a whole cell catalyst for carrying out the method and to the use of such a whole cell catalyst for oxidizing a secondary alcohol.