Method for catalytically synthesizing 1,2,3-triazole compound by using carboxylation nano-hydroxyapatite and cuprous oxide as catalytic systems

The invention discloses a method for catalytically synthesizing a 1,2,3-triazole compound by using carboxylation nano-hydroxyapatite and cuprous oxide as catalytic systems. According to the technical scheme, the method for catalytically synthesizing the 1,2,3-triazole compound by using the carboxyla...

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Hauptverfasser: LI XIAOYAN, FAN XIAOSHAN, HU ZHIGUO, ZHANG WEIWEI, ZHANG DELONG, JIANG YUQIN, HU GAICEN, ZHANG XUEXUE, PU XINMING, CAI PENGFEI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a method for catalytically synthesizing a 1,2,3-triazole compound by using carboxylation nano-hydroxyapatite and cuprous oxide as catalytic systems. According to the technical scheme, the method for catalytically synthesizing the 1,2,3-triazole compound by using the carboxylation nano-hydroxyapatite and the cuprous oxide as the catalytic systems is characterized in that a terminal alkyne compound and organic azide which are used as raw materials are mixed and stirred and react by using the carboxylation nano-hydroxyapatite and the cuprous oxide as the catalytic systems and water as a solvent under a room temperature condition so as to prepare the 1,2,3-triazole compound. The method has the advantages that the catalytic systems are simple, convenient to operate and wide in application range and can be repeatedly used, the carboxylation nano-hydroxyapatite is non-toxic, harmless, green, environmentally friendly and easy to treat after reaction and can be recycled, and the method is carried out under conditions of normal pressure and temperature, is economic and environmentally friendly and is a high-efficiency green method for preparing the 1,2,3-triazole compound.