Daphne genkwa extracts, and pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis

The present invention relates to Daphne genkwa extracts and to a pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis, expressed in the following chemical formula 1. More particular...

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Hauptverfasser: AHN KYUNG SEOP, SONG JAE SUNG, KANG HO BUM, KIM JAE WHA, GO JAE JONG, KIM JOO HEON, OH HYUN WOO, JI DA JUNG, SUN JANG MI, OH SEI RYANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to Daphne genkwa extracts and to a pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis, expressed in the following chemical formula 1. More particularly, Daphne genkwa extracts, fractions thereof, or Genekwadapnin or yuanhuacine, which are compounds separated from the extracts, may effectively increase the secretion of immune cell Th1 cytokine and may exhibit inhibitory effects on atopic dermatitis in an atopic dermatitis mouse model, and therefore, may be valuably used in the prevention or treatment of atopic dermatitis.