Use and related medicine of human IFITM3 gene

The invention discloses use and a related medicine of a human IFITM3 gene and discloses use of the human IFITM3 gene in tumor treatment, tumor diagnose and medicine preparation. The invention further constructs a human IFITM3 gene micro-molecule interfering RNA (Ribose Nucleic Acid), a human IFITM3...

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Hauptverfasser: SUN QIN, GU XUEFENG, HAN HAIXIONG, JIN YANGSHENG, YANG MIN, QU HONGHUA, CAO YUEQIONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses use and a related medicine of a human IFITM3 gene and discloses use of the human IFITM3 gene in tumor treatment, tumor diagnose and medicine preparation. The invention further constructs a human IFITM3 gene micro-molecule interfering RNA (Ribose Nucleic Acid), a human IFITM3 gene interfering nucleic acid construct as well as human IFITM3 gene interfering lentivirus and use of the three. The siRNA (micro-molecule interfering RNA), nucleic acid construct containing the siRNA or lentivirus provided by the invention can be used for specifically inhibiting the expression of the human IFITM3 gene, especially the lentivirus can be used for effectively infecting target cells, efficiently inhibiting the expression of the IFITM3 gene in the target cells, further inhibiting the growth of the tumor cells and promoting the apoptosis of tumor cells, and has important meaning in tumor treatment.