Handheld device for electrophysiological analysis

A handheld device for analysis of electrophysiological properties of a cellular membrane ion channel in an ion channel containing lipid cellular membrane includes a handheld body with a pump, an electronic controller, and a disposable pipette tip including a pathway for fluid. The pathway connects a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BYRNE NICHOLAS, MATHES CHRISTOPHER, HENNEKE JENS, KUTCHINSKY JONATAN
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A handheld device for analysis of electrophysiological properties of a cellular membrane ion channel in an ion channel containing lipid cellular membrane includes a handheld body with a pump, an electronic controller, and a disposable pipette tip including a pathway for fluid. The pathway connects an open end of the pipette tip to an analysis substrate in the pipette tip. The substrate is adapted to transmit an electrical current through the ion channel. The handheld body and the disposable pipette tip are configured to releasably attach the pipette tip to the body, to provide a hydraulic connection between the pump and the pathway, and to provide an electric connection between the electronic controller and at least one of the electrodes of the substrate. The electronic controller of the handheld body is configured to operate the assembled device for microfluidic analysis of aspirated fluid.