Discectomy devices and related methods

A tissue removal device may comprise a handheld housing, a motor, and a tissue removal mechanism coupled to the handheld housing. The tissue removal mechanism may comprise a tissue collection chamber coupled to a distal portion of the handheld housing, a jaw member comprising first and second jaw portions, where the first jaw portion is coupled to a first elongated member and the second jaw portion is coupled to a second elongated member configured to actuate the second jaw portion, a rotatable shaft disposed within a lumen of the first elongated member, a helical member disposed around at least a portion of the rotatable shaft, and an impeller coupled to at least one of a distal end of the helical member and a distal end of the rotatable shaft. Rotation of the rotatable shaft may effect rotation of the helical member and the impeller.