Device and method for using both single molecular force spectroscope and magnetic tweezers on basis of glass micro needle

The invention provides a device for using both a single molecular force spectroscope and magnetic tweezers on the basis of a glass micro needle. The device comprises a microscopic imaging device, a sample table, a sample pool and a central monitor, wherein the sample pool comprises a glass slide and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHENG CHAO, RAN SHIYONG, WEI QIANG, YANG GUANGSHEN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a device for using both a single molecular force spectroscope and magnetic tweezers on the basis of a glass micro needle. The device comprises a microscopic imaging device, a sample table, a sample pool and a central monitor, wherein the sample pool comprises a glass slide and a sample pool body; a force measuring micro needle is arranged in a force measuring groove in the sample table, is connected into a solution cavity through a square groove in the upper end of the sample pool and is sealed; an operation micro needle is arranged in an operation groove in the sample table, is connected into the solution cavity through a first square groove of the sample pool and is sealed; the operation micro needle is arranged on a needle holding device; the interior of the needle holding device is fully filled with water and is connected with an injector through a silicone tube; the needle holding device is fixedly arranged on a micro operation instrument; the micro operation instrument can move th