Regulation and optimization apparatus for protein crystallization

The invention relates to an apparatus of regulating and optimizing protein crystallization experiments by using a plurality of means. The apparatus comprises a protein solution pool, a precipitant solution pool, a quality sensor, a microscope, and a water circulation insulation cover. The apparatus...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SHU ZHANYONG, HU JIANQI, BI RUCHANG, FU SHIMI, CANG HUAIXING, JIANG PIDONG, DONG JING, DUAN BINGYA
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to an apparatus of regulating and optimizing protein crystallization experiments by using a plurality of means. The apparatus comprises a protein solution pool, a precipitant solution pool, a quality sensor, a microscope, and a water circulation insulation cover. The apparatus uses modular combination to design a protein crystallization chamber, the protein solution pool and the precipitant solution pool are all independent modules, and distances of the two pools can be adjusted. The protein solution pool is located on a support, and quality change of the protein solution pool can be transmitted to the quality sensor with sensitivity higher than ten thousandth of a gram and then is quantitatively recorded. A baffle plate with adjustable hole size is mounted between the two solution pools, and a movable transparent glass block is arranged on top of the crystallization chamber so as to adjust a volume of a vapor phase. Meanwhile, the apparatus is provided with self light sources of a white