Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin

Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin

The invention discloses a preparation method for an idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin. The preparation method comprises the following steps: dissolving beta-cyclodextrin in distilled water to prepare a saturated solution, heating the saturated solution of beta-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHENG CHUANSHEN, LIANG JUAN, CHEN YIPING, ZHU JIELIAN
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator CHENG CHUANSHEN
LIANG JUAN
CHEN YIPING
ZHU JIELIAN
description The invention discloses a preparation method for an idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin. The preparation method comprises the following steps: dissolving beta-cyclodextrin in distilled water to prepare a saturated solution, heating the saturated solution of beta-cyclodextrin to a temperature of 30 to 80 DEG C in a water bath and carrying out isothermal stirring for 15 to 50 min; adding idebenone under the condition of isothermal stirring, continuing stirring to realize uniform mixing so as to obtain a mixed solution and subjecting the mixed solution to ultrasonic inclusion so as to obtain a beta-cyclodextrin-idebenone inclusion solution; and standing the beta-cyclodextrin-idebenone inclusion solution at a temperature of 0 to 8 DEG C for 24 h, carrying out pumping filtration and drying to obtain solid powder, grinding the solid powder into fine powder and carrying out sieving so as to obtain the beta-cyclodextrin-idebenone microcapsule. The preparation method provided by th
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN103251570A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN103251570A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN103251570A3</originalsourceid><addsrcrecordid>eNqNyzEKwkAQQNE0FqLeYTxAIDEEawmKlVjYh8lmNAubmWV2FsztRfAAVr95f130d6WIiuaFYSabZISnKPiRBmJhgtk7FYcx5UBgk0p-TZCDKSZh78CzCzl992GBgQxLt7ggI71NPW-L1RNDot2vm2J_OT-6a0lRekoRHTFZ393qqjm0dXusTs0_5gMlUz4o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin</title><source>esp@cenet</source><creator>CHENG CHUANSHEN ; LIANG JUAN ; CHEN YIPING ; ZHU JIELIAN</creator><creatorcontrib>CHENG CHUANSHEN ; LIANG JUAN ; CHEN YIPING ; ZHU JIELIAN</creatorcontrib><description>The invention discloses a preparation method for an idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin. The preparation method comprises the following steps: dissolving beta-cyclodextrin in distilled water to prepare a saturated solution, heating the saturated solution of beta-cyclodextrin to a temperature of 30 to 80 DEG C in a water bath and carrying out isothermal stirring for 15 to 50 min; adding idebenone under the condition of isothermal stirring, continuing stirring to realize uniform mixing so as to obtain a mixed solution and subjecting the mixed solution to ultrasonic inclusion so as to obtain a beta-cyclodextrin-idebenone inclusion solution; and standing the beta-cyclodextrin-idebenone inclusion solution at a temperature of 0 to 8 DEG C for 24 h, carrying out pumping filtration and drying to obtain solid powder, grinding the solid powder into fine powder and carrying out sieving so as to obtain the beta-cyclodextrin-idebenone microcapsule. The preparation method provided by th</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130821&amp;DB=EPODOC&amp;CC=CN&amp;NR=103251570A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130821&amp;DB=EPODOC&amp;CC=CN&amp;NR=103251570A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHENG CHUANSHEN</creatorcontrib><creatorcontrib>LIANG JUAN</creatorcontrib><creatorcontrib>CHEN YIPING</creatorcontrib><creatorcontrib>ZHU JIELIAN</creatorcontrib><title>Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin</title><description>The invention discloses a preparation method for an idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin. The preparation method comprises the following steps: dissolving beta-cyclodextrin in distilled water to prepare a saturated solution, heating the saturated solution of beta-cyclodextrin to a temperature of 30 to 80 DEG C in a water bath and carrying out isothermal stirring for 15 to 50 min; adding idebenone under the condition of isothermal stirring, continuing stirring to realize uniform mixing so as to obtain a mixed solution and subjecting the mixed solution to ultrasonic inclusion so as to obtain a beta-cyclodextrin-idebenone inclusion solution; and standing the beta-cyclodextrin-idebenone inclusion solution at a temperature of 0 to 8 DEG C for 24 h, carrying out pumping filtration and drying to obtain solid powder, grinding the solid powder into fine powder and carrying out sieving so as to obtain the beta-cyclodextrin-idebenone microcapsule. The preparation method provided by th</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyzEKwkAQQNE0FqLeYTxAIDEEawmKlVjYh8lmNAubmWV2FsztRfAAVr95f130d6WIiuaFYSabZISnKPiRBmJhgtk7FYcx5UBgk0p-TZCDKSZh78CzCzl992GBgQxLt7ggI71NPW-L1RNDot2vm2J_OT-6a0lRekoRHTFZ393qqjm0dXusTs0_5gMlUz4o</recordid><startdate>20130821</startdate><enddate>20130821</enddate><creator>CHENG CHUANSHEN</creator><creator>LIANG JUAN</creator><creator>CHEN YIPING</creator><creator>ZHU JIELIAN</creator><scope>EVB</scope></search><sort><creationdate>20130821</creationdate><title>Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin</title><author>CHENG CHUANSHEN ; LIANG JUAN ; CHEN YIPING ; ZHU JIELIAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN103251570A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2013</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHENG CHUANSHEN</creatorcontrib><creatorcontrib>LIANG JUAN</creatorcontrib><creatorcontrib>CHEN YIPING</creatorcontrib><creatorcontrib>ZHU JIELIAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHENG CHUANSHEN</au><au>LIANG JUAN</au><au>CHEN YIPING</au><au>ZHU JIELIAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin</title><date>2013-08-21</date><risdate>2013</risdate><abstract>The invention discloses a preparation method for an idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin. The preparation method comprises the following steps: dissolving beta-cyclodextrin in distilled water to prepare a saturated solution, heating the saturated solution of beta-cyclodextrin to a temperature of 30 to 80 DEG C in a water bath and carrying out isothermal stirring for 15 to 50 min; adding idebenone under the condition of isothermal stirring, continuing stirring to realize uniform mixing so as to obtain a mixed solution and subjecting the mixed solution to ultrasonic inclusion so as to obtain a beta-cyclodextrin-idebenone inclusion solution; and standing the beta-cyclodextrin-idebenone inclusion solution at a temperature of 0 to 8 DEG C for 24 h, carrying out pumping filtration and drying to obtain solid powder, grinding the solid powder into fine powder and carrying out sieving so as to obtain the beta-cyclodextrin-idebenone microcapsule. The preparation method provided by th</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN103251570A
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Preparation method for idebenone microcapsule through ultrasonic inclusion by beta-cyclodextrin
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T13%3A39%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHENG%20CHUANSHEN&rft.date=2013-08-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN103251570A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true