Piperazine or piperidine compound as well as salts, intermediates, preparation method and application thereof

The invention discloses a piperazine or piperidine compound or salts thereof. The invention also discloses a preparation method of formula I and the preparation method comprises the step of condensing formula II and R7H in a solvent at the temperature of 10-30 DEG C under the action of alkali. The invention also discloses a preparation method of the salts of the formula I, comprising the steps of when formula VII and formula IR3 =H, F or NO2, sequentially carrying out amino protection reaction on the formula II to obtain formula V, carrying out ester hydrolysis on the formula V to obtain formula VI, carrying out condensation reaction on the formula VI and the R7H to obtain formula VII and carrying out deprotection and salification on the formula VII, wherein when formula VIIR3=NO2 and the formula IR3=NH2, the method also comprises the step of nitro reduction after the step of condensation and before the step of deprotection and salification. The invention also discloses a preparation method of intermediates i