Pentapeptide, polypeptide, cyclopeptide derivative, compound and medicament and application of pentapeptide

The invention discloses a pentapeptide, a polypeptide using the pentapeptide as an active center, a cyclopeptide derivative, a compound, an immunosuppressive medicament using the pentapeptide as an active center and application of the pentapeptide in the immunosuppressive medicament. The thymic immu...

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Bibliographische Detailangaben
Hauptverfasser: CAO JICHAO, WANG FENGSHAN, LIAN QIANQIAN, CHENG YANNA, WANG AIJUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a pentapeptide, a polypeptide using the pentapeptide as an active center, a cyclopeptide derivative, a compound, an immunosuppressive medicament using the pentapeptide as an active center and application of the pentapeptide in the immunosuppressive medicament. The thymic immunosuppressive pentapeptide (TIPP) is from low molecular weight-thymic immunosuppressive extract-c (LMW-TISE-c) and has an amino acid sequence Ala-Glu-Trp-Cys-Pro shown in SEQ ID NO. 1. The pentapeptide is a component determined by acquiring a structure from the thymic immunosuppressive component for the first time over the years. The pentapeptide is from TISE, and can be used for preparing the immunosuppressive medicament.