Preparation method of moxifloxacin hydrochloride

The invention relates to the field of moxifloxacin composition, in particular to a preparation method of moxifloxacin hydrochloride. The method comprises the steps of using a formula I chemical compound and a formula II chemical compound as starting materials, generating 1-cyclopropyl-6-fluorin-8-methoxy group-7-[(4aS,7aS)-1-t-butyloxycarboryl-octahydro-6H- pyrrolo [3,4-b] pyridine-6-base ]-4-oxygen-1, 4-EEDQ-3-carboxylate radical-boron-acetic anhydride or 1-cyclopropyl-6-fluorin-8-methoxy group-7-[(4aS,7aS)-1-t-butyloxycarboryl-octahydro-6H- pyrrolo [3,4-b] pyridine-6-base ]-4-oxygen-1, 4-EEDQ-3-carboxylate radical-boron-malonic anhydride, respectively carrying out hydrolyzation and deprotection to obtain moxifloxacin free alkali, and and eventually obtaining the moxifloxacin hydrochloride through the composition of the moxifloxacin and hydrochloric acid. According to the preparation method of the moxifloxacin hydrochloride, the starting materials are stable in properties, the used solvent can be directly re