Application of stilbene compounds in treating and preventing AIDS

The invention provides an application of stilbene compounds in treating and preventing AIDS. The stilbene compounds have a structural formula represented by the general formula (I), wherein R1, R2, R3, R4, R5 or R6 independently represents hydrogen, hydroxyl, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 acyloxy...

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Hauptverfasser:	YANG CHENG, GUO YU, RAO ZIHE, FENG JINLEI, TANG YANTING, ZHANG TANJIE, LI JINNAN, CHEN WEIQIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides an application of stilbene compounds in treating and preventing AIDS. The stilbene compounds have a structural formula represented by the general formula (I), wherein R1, R2, R3, R4, R5 or R6 independently represents hydrogen, hydroxyl, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 acyloxy, halogen, nitro, trifluoromethyl, or cyano, provided that at least one of R1, R2 and R3 is hydroxyl and at least one of R4, R5 and R6 is hydroxyl. In the compounds represented by the general formula (I), the inhibition activity IC50 of a stilbene compound piceatannol against HIV-1 protease reaches 59mum.