Antifungal derivatives of piperazine, as well as preparation method and application thereof

The invention belongs to the technical field of antifungal medicines, and provides piperazine derivatives with structures as shown in a formula I, and pharmaceutically acceptable salts of the piperazine derivatives. The definition of the R1 is in line with the description of the specifications. The invention also relates to a preparation method of the compounds, and also discloses pharmaceutical compositions which adopt the compounds or the pharmaceutically acceptable salts as the effective and active components, and application of the compounds or the pharmaceutically acceptable salts in service of antifungal medicines.